Colts 45, Bengals 37
CINCINNATI -- Peyton Manning threw for 365 yards and three touchdowns as Indianapolis maintained its unblemished record with a wild 45-37 victory over Cincinnati in a key AFC clash at Paul Brown Stadium. Manning completed 24-of-40 passes with an interception and the Colts (10-0) put up touchdowns on their first five drives en route to becoming the NFL's first team since the 1998 Denver Broncos to win its first 10 games. Dallas Clark had a career-high 125 receiving yards on six catches along with a score, while Reggie Wayne grabbed five passes for 117 yards, including a 66-yard touchdown in the first quarter. The Bengals (7-3) racked up 492 total yards and got outstanding offensive performances from Carson Palmer and Chad Johnson, but their defense offered little resistance to Indianapolis' high-powered attack. Palmer went 25-of-38 for 335 yards with two touchdowns and a pick, while Johnson compiled a personal-best 189 yards on eight receptions, including a 68-yard score.

Cardinals 38, Rams 28
ST. LOUIS -- Kurt Warner haunted his former team by completing 27-of-39 passes for 285 yards with three touchdowns, as Arizona downed St. Louis, 38-28, at Edward Jones Dome. Anquan Boldin and Larry Fitzgerald were the recipients of Warner's big day. Boldin ended with eight catches for 105 yards with a score while Fitzgerald had nine receptions for 104 yards with a touchdown for the Cardinals (3-7), who put an end to a three-game losing streak. Marc Bulger was 19-of-24 for 224 yards with two touchdowns before leaving in the fourth quarter for the Rams (4-6), who have dropped two straight games. Bulger was sacked by Adrian Wilson and landed on his right shoulder. He was taken to the locker room for x-rays where it was diagnosed as a bruised shoulder and he is listed as day-to- day. Jamie Martin filled in for Bulger and was 14-of-19 for 161 yards with a score.

Bears 13, Panthers 3
CHICAGO -- Kyle Orton threw a touchdown pass and Chicago's defense took advantage of two critical Carolina turnovers, as the Bears downed the Panthers, 13-3, in a key NFC battle at Soldier Field. Orton ended 15- of-26 for 136 yards with an interception for the Bears (7-3), who have won six straight games and have not lost since a 20-10 setback at Cleveland on October 9. Thomas Jones contributed 87 rushing yards in the win. Jake Delhomme finished 22-of-38 for 235 yards with a pair of interceptions for the Panthers (7-3), who had a six-game winning streak snapped. Steve Smith was Delhomme's favorite target, catching a season-high 14 balls for 169 yards in the setback. Carolina was trying to tie its franchise-best winning streak of seven games, set in 1996. The loss also dropped the Panthers into a first place tie in the NFC South with Tampa Bay, which defeated Atlanta on Sunday.

Cowboys 20, Lions 7
IRVING, Texas -- Marion Barber scored two touchdowns and Julius Jones rushed for 92 yards, as the Dallas Cowboys defeated the Detroit Lions, 20-7, at Texas Stadium. Barber added 53 yards on the ground for the Cowboys (7-3), who have now won three straight games and remain tied with the New York Giants for first place in the NFC East.The Giants defeated the Philadelphia Eagles, 27-17, on Sunday. Drew Bledsoe was 12-of-23 for 110 yards and Keyshawn Johnson hauled in five passes for 37 yards in the victory. Joey Harrington completed 17-of-25 passes for 169 yards in Detroit's third loss in its last four games. Kevin Jones added a touchdown for the Lions (4-6), but had only 29 yards rushing. The Cowboys led the entire game and controlled the time of possession, 36:02 to Detroit's 23:58.

Jaguars 31, Titans 28
NASHVILLE, Tenn. -- Byron Leftwich overcame a sluggish start to throw three touchdown passes, leading the Jacksonville Jaguars to a 31-28 victory over the Tennessee Titans at The Coliseum. Leftwich, who misfired on his first seven passes, finished 22-of-38 for 258 yards. He also ran for a score as the Jaguars (7-3) won their third straight game. After going 58 consecutive games without scoring 30 points, Jacksonville has reached that mark each of the past two weeks. The Jaguars did it without much of rushing game, managing just 49 yards on 30 attempts for a 1.6-yard average. Fred Taylor started the game for Jacksonville despite being listed as doubtful all week with an ankle injury, but he was ineffective with minus-eight yards on six carries -- all in the first half. Steve McNair threw for 208 yards with a pair of touchdowns and one interception for the Titans (2-8), who have lost five in a row. Chris Brown ran for 61 yards and a touchdown on 20 carries and caught four passes for 58 yards with a score in defeat.

Browns, Dolphins 0
CLEVELAND -- Reuben Droughns scored on a 75-yard run on Cleveland's first play of the game and finished with 166 rushing yards, as the Browns posted a 22-0 victory over the Miami Dolphins. Trent Dilfer added a touchdown pass and Phil Dawson booted three field goals for the Browns (4-6), who won for the second time in three games. Cleveland held Miami to just 194 total yards and earned its first shutout in nearly four years. The Dolphins (3-7) lost their third straight game and fell for the sixth time in their last seven outings. Sage Rosenfels got the start at quarterback for Miami because Gus Frerotte was bothered by an injured throwing finger, but the second start of Rosenfels' career was short-lived. He was replaced early in the third quarter after completing just 5-of-10 passes for a mere 14 yards with a pair of interceptions. Frerotte was just as bad in relief, completing only 4-of-18 throws for 53 yards.

Patriots 24, Saints 17
FOXBORO, Mass. -- Tom Brady threw three touchdown passes to lead the New England Patriots to a 24-17 victory over the New Orleans Saints at Gillette Stadium. Brady completed 15-of-29 passes for 222 yards for the Patriots (6-4), who have won two straight for the first time this season. New England won despite yielding 425 yards to New Orleans. Patriots head coach Bill Belichick was on the sideline despite learning of his father's death Saturday night. Aaron Brooks threw for 343 yards with a pair of touchdowns on 27-of-50 passing for the Saints (2-8), who were coming off their bye week. New Orleans has lost six in a row. The Patriots played without running back Corey Dillon, who was sidelined with a strained calf. Heath Evans, who filled in nicely during last week's 23-16 victory over Miami, finished with 74 yards on 16 carries Sunday. Patrick Pass added 53 yards on 13 attempts and also caught two passes for 36 yards.

Radiers 16, Redskins 13
WASHINGTON, D.C. -- Sebastian Janikowski nailed a 19-yard field goal with 1:08 remaining in the game and Derrick Burgess posted a huge sack to halt a late Washington rally, as the Oakland Raiders posted a 16-13 win over the Redskins at FedEx Field. Kerry Collins completed 19 of his 36 attempts for 289 yards with a touchdown and an interception for the Raiders (4-6), who ended a two-game losing streak. Jerry Porter caught six passes for a season-high 142 yards and a score in the win, while Lamont Jordan chipped in 52 yards rushing and 37 yards receiving. The Raiders have won four of the last five meetings with Washington. Lemar Marshall had a 17-yard interception return for a touchdown and John Hall kicked two field goals, as Washington (5-5) dropped its second straight game and third in four weeks.

Giants 27, Eagles 17
EAST RUTHERFORD, N.J. -- Eli Manning threw three touchdown passes to lead the New York Giants past the Philadelphia Eagles, 27-17, in an NFC East showdown at Giants Stadium. Plaxico Burress hauled in six passes for 113 yards and a touchdown for the Giants (7-3), who remain tied atop the division with Dallas. The Cowboys defeated the Detroit Lions on Sunday afternoon. Tiki Barber ran for 112 yards on 21 carries in the win for the Giants, who rebounded from last Sunday's debacle against Minnesota to win for the fourth time in five weeks. Eagles quarterback Mike McMahon started Sunday's game in place of Donovan McNabb, who was out with a groin injury and sports hernia. McMahon, in his eighth NFL start, had an erratic first half but settled down to complete 18 of his 39 attempts for 298 yards with a touchdown and an interception. McMahon also ran for a score. Brian Westbrook had 66 yards rushing and 57 yards receiving for Philadelphia (4-6), which suffered its fourth straight loss.

Buccaneers 30, Atlanta 27
ATLANTA -- Matt Bryant kicked a 45-yard field goal with 42 seconds remaining, lifting the Tampa Bay Buccaneers over the Atlanta Falcons, 30-27, at the Georgia Dome. Cadillac Williams rushed for 116 yards and a touchdown on 19 carries for the Bucs (7-3), who have won their last two games by a combined four points. With the win, Tampa moved into a first-place tie in the NFC South with Carolina, which lost to Chicago Sunday. Chris Simms finished 11-of-19 for 118 yards with an interception, and Michael Clayton led all Tampa receivers with three catches for 48 yards. Michael Vick went 21- of-38 for 306 yards and two touchdowns for Atlanta (6-4), which has lost two straight to slip to third in the competitive NFC South. Roddy White was Vick's top target, hauling in four passes for 108 yards.

Ravens 16, Steelers 13 (OT)
BALTIMORE, Md. -- Matt Stover kicked a 44-yard field goal with 4:09 remaining in overtime to give the Baltimore Ravens a 16-13 victory over the Pittsburgh Steelers at M&T Bank Stadium. Kyle Boller completed 21-of-36 passes for 163 yards and his first touchdown of the season for the Ravens (3-7), who snapped a four-game losing streak. Chester Taylor received the bulk of the carries, especially during the fourth quarter and overtime, and ran for 59 yards while catching four passes for 26 yards. Tommy Maddox, filling in for injured quarterbacks Ben Roethlisberger and Charlie Batch, was 19-of-36 for 230 yards with a touchdown and an interception. Hines Ward caught six passes for 81 yards and Willie Parker ran for 59 yards and caught a TD pass for Pittsburgh (7-3), which had a four-game winning streak snapped.

Seahawks 27, 49ers 25
SAN FRANCISCO -- Shaun Alexander rushed for 115 yards with two touchdowns as the Seattle Seahawks held on to defeat the San Francisco 49ers, 27-25, at Monster Park. Alexander now has over 1,200 yards on the ground for the third consecutive season. Matt Hasselbeck was 19- of-31 for 233 yards and a touchdown as the Seahawks (8-2) won their sixth straight game. Bobby Engram caught six passes for 93 yards in the win. Ken Dorsey completed 18-of-29 passes for 249 yards and a touchdown, as San Francisco (2-8) broke a 15-quarter drought without a touchdown. The dry spell lasted over 200 minutes and 47 possessions. Maurice Hicks carried the ball 11 times for 83 yards and a score for the Niners, who have now lost three straight games. Seattle has now defeated San Francisco in five consecutive meetings.

Chargers 48, Bills 10
SAN DIEGO -- Drew Brees completed 28-of-33 passes for 339 yards with four touchdowns, as San Diego showed no rust following its bye week by blasting Buffalo, 48-10, at Qualcomm Stadium. LaDainian Tomlinson rushed for 67 yards and a score on 19 carries for the Chargers (6-4), who have won three straight games. Keenan McCardell added six catches for 88 yards with a score while Antonio Gates hauled in five passes for 77 yards and a TD in the win. Gates, though, left in the third quarter with a foot injury and did not return. J.P. Losman got the start and ended 20-of-36 for 168 yards with a touchdown and an interception for the Bills (4-6), who have dropped three of their past four contests. Losman provided a big lift when he came in off the bench during last week's win over Kansas City after Kelly Holcomb left with a head injury, but was not nearly as sharp in this one.

Broncos 27, Jets 0
DENVER -- Mike Anderson erupted for 113 rushing yards and three touchdowns, as the Denver Broncos crushed the New York Jets, 27-0, at Invesco Field. Jake Plummer went 18-of-26 for 225 yards for Denver (8-2), which has won three straight and maintains a two-game advantage in the AFC West. Ashley Lelie led all receivers with four catches for 81 yards in the win. The Broncos defense forced five turnovers in the game and held the Jets to 195 total yards. New York quarterback Brooks Bollinger suffered a head injury in the first quarter and was replaced by Vinny Testaverde, who went 15-of-25 for 152 yards with two interceptions and three fumbles. Testaverde left the game as well in the waning moments with an apparent leg injury, allowing Kliff Kingsbury to throw his first NFL pass. Justin McCareins was the team's leading rusher with eight yards on one attempt for the Jets (2-8), who have lost five straight games.

Chiefs 45, Texans 17
HOUSTON -- Larry Johnson ran for a club-record 211 yards on 36 carries along with a pair of scores, while Trent Green threw three touchdown passes as Kansas City routed lowly Houston, 45-17, at Reliant Stadium. Green rebounded strongly from a subpar outing in last week's 14-3 loss at Buffalo, completing 19-of-29 passes for 220 yards with an interception for the Chiefs (6-4). Two of his TD passes went to Eddie Kennison, who finished with four receptions for 57 yards. Tony Gonzalez added nine catches for 98 yards in the win. Johnson broke Barry Word's single-game record of 200 yards set October 14, 1990 at Detroit. Domanick Davis compiled 110 total yards, including 53 receiving on three grabs, and scored once on the ground for the Texans (1-9). David Carr threw for 182 yards with an interception on 19-of-36 passing in the loss, Houston's third in a row. Jerome Mathis had a Texans' record 99-yard kickoff return in the first quarter.

Vikings 20, Packers 17 (Monday night)
GREEN BAY, Wis. -- Paul Edinger kicked a 27-yard field goal as time expired to lift the Minnesota Vikings to a 20-17 win over the Green Bay Packers on Monday night at Lambeau Field. Mewelde Moore ran for 122 yards on 22 carries and Brad Johnson improved to 3-0 as a starter this season, completing 18-of-30 passes for 196 yards for the Vikings (5-5), who have won three straight and will host the Cleveland Browns next Sunday. Devonte Edwards had a 51-yard interception return for a score in the win. Brett Favre completed 20-of-33 passes for 227 yards and a pair of TDs, but was intercepted twice for the Packers (2-8), losers of four of their last five games. Donald Driver caught both of Favre's touchdown strikes and ended with 84 yards on five receptions. Green Bay, which was held to 21 rushing yards, will travel to Philadelphia next weekend.