BOSTON -- Boston's tough new anti-smoking laws -- some of the strictest in the nation -- went into effect Monday.

At college campus stores and at about 75 pharmacies, including those in supermarkets, all tobacco products must come off shelves.

Boston's Public Health Commission has also ordered that there can be no smoking in hotels, inns or bed & breakfasts. It is also prohibited in outdoor areas around the workplace, such as patios and loading docks.

Already, smoking is prohibited on the patios of restaurants and bars with outdoor service.

One of the most controversial provisions is the ban on new smoking bars, such as hookah and cigar bars, with current bar owners told they must be out of business in 10 years.

The commission's executive director Barbara Ferrer quoted a statistic that shows smoking killing more people in the U.S. than alcohol, murder and suicide combined.

Tobacco is the leading cause of preventable death in the U.S., health officials said.

Smoking bar supporters, however, said tobacco is not yet illegal in the U.S. and the city has no right to regulate the items.

Boston is the second city in the country to ban the sale of cigarettes in pharmacies.