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2008 McNeese State Cowboys Schedule
| Date | Time (ET) | Opponent | Result | Record |
| 08/30/2008 | 06:00 PM | at North Carolina | L, 35-27 | 0-1-0 |
| 09/06/2008 | 08:00 PM | Delta State | W, 52-27 | 1-1-0 |
| 09/13/2008 | 08:00 PM | Cal Poly | ||
| 09/27/2008 | 08:00 PM | So Virginia | W, 63-7 | 2-1-0 |
| 10/04/2008 | 03:00 PM | at South Dakota St | W, 46-44 | 3-1-0 |
| 10/11/2008 | 08:00 PM | Texas State | L, 45-42 | 3-2-0 |
| 10/18/2008 | 03:00 PM | at Sam Houston St | W, 28-17 | 4-2-0 |
| 10/25/2008 | 08:00 PM | Nicholls State | L, 38-35 | 4-3-0 |
| 11/01/2008 | 07:00 PM | at SE Louisiana | W, 24-14 | 5-3-0 |
| 11/08/2008 | 08:00 PM | Stephen F Austin | W, 42-31 | 6-3-0 |
| 11/15/2008 | 07:00 PM | at Northwestern St | W, 24-17 | 7-3-0 |
| 11/22/2008 | 05:00 PM | at Central Arkansas | L, 47-30 | 7-4-0 |
McNeese State
Scoreboard |
